Rutgers University Cell and DNA Repository Adopts BioLife Solutions CryoStor™ as Standard Biopreservation Media
Decision Based on Improved Recovery and Elimination of Serum in Cryopreservation of Cell Lines Used in Worldwide Disease Research Efforts
PRNewswire-FirstCall
BOTHELL, Wash.

BioLife Solutions, Inc. (BULLETIN BOARD: BLFS) , a leading developer and marketer of proprietary cGMP hypothermic storage and cryopreservation media products for cells, tissues, and organs, today announced that the Rutgers University Cell and DNA Repository (RUCDR), the world's largest university-based biologics repository, has adopted the Company's CryoStor as the exclusive cryopreservation media for its transformed lymphocyte cell lines (LCL), which are used throughout the world by researchers working to find genetic causes of common, complex diseases such as alcohol/addiction, diabetes, autism, and numerous mental disorders.

Douglas A. Fugman, Ph.D., Managing Director of RUCDR, explained the decision to transition from an in-house formulated media containing culture media and fetal bovine serum to CryoStor by stating, "We continually strive to optimize our cell processing protocols to improve the quality of the cell lines we make available to researchers around the world. Our technical evaluation clearly indicated that CryoStor offered advantages in post- preservation cell recovery and we view pre-formulated, serum and protein free CryoStor as the best-in-class biopreservation media for cell banking applications."

Mike Rice, BioLife's chairman and CEO, noted, "We view this product adoption by RUCDR as further validation that our initiative to raise the quality and regulatory bar for biopreservation media products is being recognized and valued in our strategic markets. Dr. Fugman's operations team processes over 36,000 cell lines annually and this represents significant volume demand for CryoStor. We expect to begin fulfilling orders in a custom package to support RUCDR within 60 days, following final validation of our internal manufacturing facility in Bothell."

About BioLife Solutions, Inc:

BioLife Solutions develops and markets patented hypothermic storage/transport and cryopreservation media products for cells, tissues, and organs. The Company's proprietary HypoThermosol® and CryoStor™ platform of biopreservation media products are marketed to academic research institutions, hospitals, and commercial companies involved in cell therapy, tissue engineering, cord blood banking, drug discovery, and toxicology testing. BioLife's cGMP products are serum-free and protein-free, fully defined, and formulated to reduce preservation-induced, delayed-onset cell damage and death. BioLife's enabling technology provides research and clinical organizations significant improvement in post-preservation cell and tissue viability and function. For more information please visit http://www.biolifesolutions.com/.

About RUCDR:

Rutgers University Cell and DNA Repository (RUCDR) is led by Scientific Director Jay A. Tischfield, Ph.D., FFACMG, and plays a key role in research aimed at understanding the genetic causes of common, complex diseases. RUCDR activities will enable gene discovery leading to diagnoses, treatments and, eventually, cures for these diseases. RUCDR assists researchers throughout the world by providing the highest quality biomaterials, technical consultation, and logistical support. RUCDR is the largest university based repository in the world, located on the Busch Campus of Rutgers University, Piscataway, New Jersey. For more information, please visit http://www.rucdr.org/.

This news release contains forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. These forward-looking statements include any statements that relate to the intent, belief, plans or expectations of the Company or its management, or that are not a statement of historical fact. Any forward-looking statements in this news release are based on current expectations and beliefs and are subject to numerous risks and uncertainties that could cause actual results to differ materially. Some of the specific factors that could cause BioLife Solutions' actual results to differ materially are discussed in the Company's recent filings with the Securities and Exchange Commission. BioLife Solutions disclaims any obligation to update any forward-looking statements as a result of developments occurring after the date of this press release.

   Media Relations:            Investor Relations:
   Len Hall                    Matt Clawson
   Allen & Caron Inc.          Allen & Caron Inc.
   (949) 474-4300              (949) 474-4300
   len@allencaron.com          matt@allencaron.com

First Call Analyst:
FCMN Contact:

SOURCE: BioLife Solutions, Inc.

CONTACT: Media, Len Hall, len@allencaron.com, or Investors, Matt Clawson,
matt@allencaron.com, both of Allen & Caron Inc., +1-949-474-4300, for BioLife
Solutions, Inc.

We believe the promise of cell and gene therapies starts with the integrity of a single cell

Advancing the future of cell and gene therapy

The human body can heal itself. Cell and gene therapies are designed to augment the patient’s ability to fight disease but only if the living cells behind those therapies remain viable and functional throughout the production processes. At BioLife Solutions, our mission is to protect the integrity of cells and provide trusted tools, services, and expertise that can enable our customers to advance the development and delivery of cell and gene therapies. We believe the future of cell and gene therapies hinges on the integrity of every single cell and we are here to protect that promise.

We understand the technical demands of bioprocessing in this field, and our advanced biopreservation expertise, cell culture optimization products, innovative storage systems, and closed-system manufacturing solutions are designed to enhance process efficiency, maintain cellular viability, and ensure reproducibility at every stage. Whether scaling up from R&D, navigating clinical trials or optimizing cryopreservation protocols for commercial production, we provide the tools and experience to streamline your workflow and safeguard your therapies.

Work with experts who understand your biopreservation challenges

Notch-Right-25px
Notch-Bottom-25px

Collaborative and comprehensive CDMO support

At BioLife Solutions, we partner with leading contract development and manufacturing organizations (CDMOs) to enhance their biopreservation and cell processing capabilities. By providing advanced tools, regulatory support, and process optimization strategies, we empower CDMOs to better serve therapy developers, ensuring quality, consistency, and scalability in cell therapy manufacturing.

Regulatory
readiness

Navigating the complex regulatory landscape of cell and gene therapy requires a proactive approach. BioLife Solutions offers experienced regulatory support to help prepare your biopreservation and cell processing methods to meet global standards. From IND and BLA submissions to compliance with GMP, FDA, and EMA guidelines, our solutions help streamline approval pathways.

Notch-Left-25px
Notch-Bottom-25px

STORE

CellSeal®
CryoCase

Alleviate CGT container challenges like fracture risk, bag burping or high rates of particulates

Notch-Right-25px
Notch-Bottom-25px

Data-driven
decision making

Stay ahead with our comprehensive Evidence Library, a curated collection of scientific publications, white papers, and case studies demonstrating the efficacy of BioLife Solutions’ technologies. Access peer-reviewed research, real-world application data, and expert insights to support your bioprocessing and regulatory strategies.

Insights

May 21, 2025

Designing the Ideal Cryostorage Container for CGT

April 18, 2025

The Cell Summit ’25: A Must-Attend Event for Innovators in Cell & Gene Therapy

March 27, 2025

Optimizing Biopreservation Strategies for Apheresis-Derived Cells in Immunotherapeutic Applications

February 19, 2025

How to prepare early for regulatory submissions from IND to BLA

Preserve, protect and expand cell performance

Mastering
Biopreservation

Ensure Regulatory Submission Readiness

Automate & Close
CGT Processes

Protect & Expand
Cell Performance